Evidenced-based Guidelines for Prevention and Treatment of Neurological Complications in Children and Adults with Sickle Cell Disease

Presented by:
Michael R. DeBaun, MD, MPH
Professor of Pediatrics and Medicine
Vice Chair for Clinical and Translational Research
J.C. Peterson Chair in Pediatric Pulmonology
Director, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease

Faculty Disclosure:
Dr. DeBraun has disclosed that he has no relevant financial relationships. No one else in a position to control content has any financial relationships to disclose. Conflict of interest information for the CME Advisory Committee members can be found on the following website: https://cme.ufl.edu/disclosure/. All relevant financial relationships have been mitigated.

Release Date: June 28, 2023
Expiration Date: June 27, 2024

Target Audience: Primary Care Physicians, Specialty Physicians (Pediatrics, Pediatric Hematology, Adult Hematology), Physician Assistants, Nurses, Pharmacists, and other clinicians involved in the care of patients with Sickle Cell Disease.

Learning Objectives:
As a result of participation in this activity, participants should be able to:

  • Describe the evidence-based strategies for primary and secondary stroke prevention
  • Describe the evidence-based strategies for acute management of strokes
  • Describe the alternative to primary and secondary stroke prevention when family does not embrace regular blood transfusions therapy
  • Describe less established secondary stroke prevention strategies revascular procedures, and curative therapy
  • Requirements for successful completion: Certificates are awarded upon successful completion (80% proficiency) of the post-test.

Accreditation: The University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit: The University of Florida College of Medicine designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Resource(s) for further study:
M. R. DeBaun, L. C. Jordan, A. A. King, J. Schatz, E. Vichinsky, C. K. Fox, R. C. McKinstry, P. Telfer, M. A. Kraut, L. Daraz, F. J. Kirkham, M. H. Murad; American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults. Blood Adv 2020; 4 (8): 1554–1588. doi: https://doi.org/10.1182/bloodadvances.2019001142

If you have any questions please feel free to contact Debbie Ringdahl at ringdd@shands.ufl.edu

Section # 2450